[Eosinophilic small vessel vasculites (EGPA) a hidden severe asthma comorbitity].
Laeknabladid
; 110(1): 28-32, 2024 01.
Article
de Is
| MEDLINE
| ID: mdl-38126794
ABSTRACT
A 72-year-old woman presented to the emergency department due to worsening dyspnea. She had been diagnosed with asthma a year earlier. At arrival, her oxygen saturation was only 84%. During lung auscultation, wheezing was noted over all lung fields. A blood test showed a significant increase in eosinophils in peripheral blood, highest value of 1.4 x 10E9/L. Further investigations in the respiratory ward showed a positive MPO-ANCA, which, together with clinical features of asthma, chronic rhinosinusitis with polyps, mononeuritis multiplex and eosinophilia, led to the diagnosis of eosinophilic granulomatosis with polyangiitis, or what used to be called Churg-Strauss syndrome. Corticosteroid treatment was initiated and subsequently tapered down when treatment with mepolizumab was started, which is an IL-5 inhibitor. Her symptoms quickly became much better. Frequent exacerbations and pulmonary symptoms became things of the past.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Asthme
/
Syndrome de Churg-Strauss
/
Granulomatose avec polyangéite
Limites:
Aged
/
Female
/
Humans
Langue:
Is
Journal:
Laeknabladid
Année:
2024
Type de document:
Article
Pays de publication:
Islande