Long-term exposure to reduced specific-size ambient particulate matter and progression of arterial stiffness among Chinese adults.
J Hazard Mater
; 466: 133482, 2024 03 15.
Article
de En
| MEDLINE
| ID: mdl-38246055
ABSTRACT
To assess the associations of ambient specific-size PM with brachial-ankle pulse wave velocity (baPWV) and the progression of arterial stiffness. Participants were included from the Kailuan study, the cross-sectional study involved 36,486 participants, while the longitudinal study enrolled 16,871 participants. PM exposures was assessed through satellite-based random forest approaches at a 1 km resolution. Initial observations indicated a link between baseline baPWV and heightened levels of PM1, PM2.5, and PM10 exposure, and greater effects were observed for PM1 (ß 22.52, 95% CI 18.14-26.89), followed by PM2.5 (ß 9.76, 95% CI 7.52-12.00), and PM10 (ß 8.88, 95% CI 7.32-10.45). Furthermore, the growth rate of baPWV was higher in participants exposed to high levels of PM1 exposure (ß 2.77, 95% CI 1.19-4.35), succeeded by PM2.5 and PM10. Throughout a median follow-up period of 4.04 years, arterial stiffness was diagnosed in 1709 subjects. Long-term exposure to PM was linked with an increased risk of incident arterial stiffness, estimated HR for fixed 10 µg/m3 increments in annual average PM1 was 2.20 (95% CI 2.01-2.42), PM2.5 was 1.48 (95% CI 1.41-1.55), and PM10 1.32 (95% CI 1.27-1.36). PM had a greater impact on men and older individuals (P for interaction <0.001). Long-term exposures to ambient PM1, PM2.5, and PM10 were positively associated with baPWV and an increased risk of arterial stiffness. Higher estimated effects were observed for PM1 than PM2.5 and PM10.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Polluants atmosphériques
/
Pollution de l'air
/
Rigidité vasculaire
Type d'étude:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limites:
Adult
/
Humans
/
Male
Pays/Région comme sujet:
Asia
Langue:
En
Journal:
J Hazard Mater
/
J. hazard. mater
/
Journal of hazardous materials
Sujet du journal:
SAUDE AMBIENTAL
Année:
2024
Type de document:
Article
Pays d'affiliation:
Chine
Pays de publication:
Pays-Bas