Comparison of performances of SIREN or MFSRS in stroke risk prediction in an African environment.
BMC Public Health
; 24(1): 368, 2024 02 05.
Article
de En
| MEDLINE
| ID: mdl-38311723
ABSTRACT
BACKGROUND:
The Modified Framingham Stroke Risk Score (MFSRS) is a widely utilized stroke risk assessment algorithm usually applied in international comparison. The Stroke Investigative Research and Educational Network (SIREN) is the only known African-specific stroke risk assessment algorithm. AIMS ANDOBJECTIVES:
To compare stroke risk estimates from the SIREN and the MFSRS in an African community.METHODS:
This was a population-based cross-sectional survey involving consecutively recruited 310 consenting adult residents (mean age = 37.21 ± 15.84 years) of a Nigerian community. Risk factors of stroke were assessed among the participants and were utilized in calculating stroke risk estimates on the MFSRS and the SIREN. The obtained data were analyzed using descriptive statistics and the Spearman-rank order correlation test at an alpha level of 0.05.RESULTS:
The percentage stroke risk scores estimated by the SIREN and the MFSRS were 34.5% and 6.79% respectively. The most prevalent risk factors among the participants were hypertriglyceridemia (100.0%), raised waist-hip ratio (50.6%), hypercholesterolemia (45.5), physical inactivity (43.2%), psychological stress (41.3%), and hypertension (37.7%). Only two (hypertriglyceridemia and high blood pressure) out of the six factors considered in the MFSRS were rated among the first 10 most impactful risks by the SIREN. There was a weak correlation between the total scores on the MFSRS and the SIREN (rho = 0.39; p < 0.01) suggesting that the two ratings were discordant.CONCLUSION:
There were disagreements between the risk estimates on the SIREN and MFSRS with SIREN having a higher estimate that corresponded with the literature; this may be suggesting a poorer estimation of stroke risks by the MFSRS in an African environment. There is a need for large African-based quality control studies to determine and address these lapses.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Accident vasculaire cérébral
/
Africains de l'Ouest
Type d'étude:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Adult
/
Humans
/
Middle aged
Pays/Région comme sujet:
Africa
Langue:
En
Journal:
BMC Public Health
Sujet du journal:
SAUDE PUBLICA
Année:
2024
Type de document:
Article
Pays d'affiliation:
Nigeria
Pays de publication:
Royaume-Uni