The favorable impacts of cardamom on related complications of diabetes: A comprehensive literature systematic review.
Diabetes Metab Syndr
; 18(2): 102947, 2024 Feb.
Article
de En
| MEDLINE
| ID: mdl-38325073
ABSTRACT
BACKGROUND AND AIM:
Complementary and alternative medicine plays an increasing role in preventing, and regulatory, complications associated with diabetes. There are plenty of polyphenolic compounds found in Elettaria cardamomum (Cardamom) such as luteolin, limonene, pelargonidin, caffeic acid, kaempferol, gallic acid, and quercetin which can be used in many metabolic diseases.METHOD:
The objective of this systematic review was to appraise evidence from clinical and in vivo studies on the effects of cardamom on inflammation, blood glucose, oxidative stress and dyslipidemia of diabetes mellitus. According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements, the present study was carried out. Studies were conducted by searching databases such as EMBASE, Scopus, PubMed, Google Scholar, web of sciences, and Cochrane Library from the commencement until April 2022.RESULTS:
All available human and animal studies examining the effects of cardamom on diabetes were published in the form of English articles. Finally, only 14 of the 241 articles met the criteria for analysis. Of the 14 articles, 8 were in vivo studies, and 6 were clinical trial studies. Most studies have indicated the beneficial effects of cardamom on insulin resistance, oxidative stress and inflammation. Cardamom also improved dyslipidemia, but had no substantial effect on weight loss.CONCLUSION:
According to most studies, cardamom supplementation enhanced antioxidant enzyme production and activity in diabetes mellitus and decreased oxidative stress and inflammatory factors. Despite this, the exact mechanism of the disease needs to be identified through more clinical trials.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Elettaria
/
Complications du diabète
/
Diabète de type 2
/
Dyslipidémies
Type d'étude:
Prognostic_studies
/
Systematic_reviews
Limites:
Animals
/
Humans
Langue:
En
Journal:
Diabetes & metabolic syndrome (Print)
/
Diabetes Metab Syndr
/
Diabetes metab. syndr
Année:
2024
Type de document:
Article
Pays d'affiliation:
Iran
Pays de publication:
Pays-Bas