Systemic xanthogranuloma involving bone marrow and skin in a case of B-Lymphoblastic Leukemia.
Indian J Pathol Microbiol
; 67(1): 185-188, 2024.
Article
de En
| MEDLINE
| ID: mdl-38358218
ABSTRACT
Juvenile xanthogranuloma is a benign self-limiting lesion commonly described in infants and young children. It most commonly involves the skin presenting as single or multiple yellowish-brown papules. Clinical scenario with the classic histomorphology showing histiocytic aggregates in the dermis with xanthomatous cytoplasm, toutan type giant cells, immunohistochemistry with positive CD68, CD163, factor XIIIa and negative CD1a and S-100 help in diagnosis. However, diagnosis becomes challenging with predominant systemic bone marrow involvement in post-B-lymphoblastic leukemia settings.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Leucémie-lymphome lymphoblastique à précurseurs B
/
Xanthomatose
/
Xanthome juvénile
/
Leucémie-lymphome lymphoblastique à précurseurs B et T
Type d'étude:
Diagnostic_studies
Limites:
Child
/
Child, preschool
/
Humans
/
Infant
Langue:
En
Journal:
Indian J Pathol Microbiol
/
Indian j. pathol. microbiol
/
Indian journal of pathology and microbiology
Année:
2024
Type de document:
Article
Pays d'affiliation:
Inde
Pays de publication:
Inde