An Update on the Pathogenesis of Fascioliasis: What Do We Know?
Res Rep Trop Med
; 15: 13-24, 2024.
Article
de En
| MEDLINE
| ID: mdl-38371362
ABSTRACT
Fasciola hepatica is a trematode parasite distributed worldwide. It is known to cause disease in mammals, producing significant economic loses to livestock industry and burden to human health. After ingestion, the parasites migrate through the liver and mature in the bile ducts. A better understanding of the parasite's immunopathogenesis would help to develop efficacious therapeutics and vaccines. Currently, much of our knowledge comes from in vitro and in vivo studies in animal models. Relatively little is known about the host-parasite interactions in humans. Here, we provide a narrative review of what is currently know about the pathogenesis and host immune responses to F. hepatica summarizing the evidence available from the multiple hosts that this parasite infects.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
Res Rep Trop Med
Année:
2024
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique