The first case report: diagnosis and management of necrotizing fusobacterium lung abscess via BALF next-generation sequencing.
BMC Infect Dis
; 24(1): 218, 2024 Feb 19.
Article
de En
| MEDLINE
| ID: mdl-38373919
ABSTRACT
BACKGROUND:
Fusobacterium necrophorum (F. necrophorum)-induced necrotizing pneumonia is a rare but severe pulmonary infection. Insufficient microbiological detection methods can lead to diagnostic difficulties.METHODS:
We report a case of F. necrophorum lung abscess diagnosed by next-generation sequencing (NGS) of bronchoalveolar lavage fluid (BALF).RESULTS:
BALF-NGS detected F. necrophorum, guiding subsequent targeted antibiotic therapy. With active drainage and metronidazole treatment, the patient's condition was effectively treated.CONCLUSION:
BALF-NGS is a valuable tool for the rapid diagnosis of infections caused by difficult-to-culture bacteria. It played a decisive role in the early identification of F. necrophorum, enabling timely and targeted antibiotic intervention. Early diagnosis and appropriate treatment are crucial for the management of F. necrophorum pneumonia.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Infections à Fusobacterium
/
Abcès du poumon
Limites:
Humans
Langue:
En
Journal:
BMC Infect Dis
Sujet du journal:
DOENCAS TRANSMISSIVEIS
Année:
2024
Type de document:
Article
Pays d'affiliation:
Chine