A diffusible small-RNA-based Turing system dynamically coordinates organ polarity.
Nat Plants
; 10(3): 412-422, 2024 03.
Article
de En
| MEDLINE
| ID: mdl-38409292
ABSTRACT
The formation of a flat and thin leaf presents a developmentally challenging problem, requiring intricate regulation of adaxial-abaxial (top-bottom) polarity. The patterning principles controlling the spatial arrangement of these domains during organ growth have remained unclear. Here we show that this regulation in Arabidopsis thaliana is achieved by an organ-autonomous Turing reaction-diffusion system centred on mobile small RNAs. The data illustrate how Turing dynamics transiently instructed by prepatterned information is sufficient to self-sustain properly oriented polarity in a dynamic, growing organ, presenting intriguing parallels to left-right patterning in the vertebrate embryo. Computational modelling demonstrates that this self-organizing system continuously adapts to coordinate the robust planar polarity of a flat leaf while affording flexibility to generate the tissue patterns of evolutionarily diverse organ shapes. Our findings identify a small-RNA-based Turing network as a dynamic regulator of organ polarity that accounts for leaf shape diversity at the level of the individual organ, plant or species.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Arabidopsis
/
Protéines d'Arabidopsis
Langue:
En
Journal:
Nat Plants
/
Nat. Plants
/
Nature plants (Online)
Année:
2024
Type de document:
Article
Pays d'affiliation:
Allemagne
Pays de publication:
Royaume-Uni