Catalyst-free visible light-promoted defunctionalization of alkyl isocyanides with a hydrosilane through C-N bond cleavage.

Ma, Yu-Qing; Tian, Shi-Kai

Ma, Yu-Qing; Tian, Shi-Kai.

Affiliation

Ma YQ; Hefei National Research Center for Physical Sciences at the Microscale, Key Laboratory of Precision and Intelligent Chemistry, and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. tiansk@ustc.edu.cn.
Tian SK; Hefei National Research Center for Physical Sciences at the Microscale, Key Laboratory of Precision and Intelligent Chemistry, and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. tiansk@ustc.edu.cn.

Org Biomol Chem ; 22(13): 2562-2565, 2024 Mar 27.

Article de En | MEDLINE | ID: mdl-38451158

ABSTRACT

ABSTRACT

A radical initiator-free defunctionalization reaction of alkyl isocyanides with a hydrosilane has been established through C-N bond cleavage under catalyst-free visible light irradiation. Various alkyl isocyanides participated in the defunctionalization with tris(trimethylsilyl)silane under blue light irradiation at room temperature, delivering the reduced products in good yields with high chemoselectivity.

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Org Biomol Chem / Org. biomol. chem / Organic & biomolecular chemistry Sujet du journal: BIOQUIMICA / QUIMICA Année: 2024 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni

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