Is it too early to recommend local treatment in oligometastatic non-small cell lung cancer: a plea for equipoise.
Br J Radiol
; 97(1157): 913-919, 2024 May 07.
Article
de En
| MEDLINE
| ID: mdl-38538948
ABSTRACT
Oligometastatic non-small cell lung cancer (OMD NSCLC) has been proposed to bridge the spectrum between non-metastatic and widely metastatic states and is perceived as an opportunity for potential cure if removed. Twelve clinical trials on local treatment have been reported, yet none are conclusive. These trials informed the development of a joint clinical practice guideline by the American & European Societies for Radiation Oncology, which endorses local treatment for OMD NSCLC. However, the heterogeneity between prognostic factors within these trials likely influenced outcomes and can only support guidance at this time. Caution against an uncritical acceptance of the guideline is discussed, as strong recommendations are offered based on expert opinion and inconclusive evidence. The guideline is also examined by a patient's caregiver, who emphasizes that uncertain evidence impedes shared decision making.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Guides de bonnes pratiques cliniques comme sujet
/
Carcinome pulmonaire non à petites cellules
/
Tumeurs du poumon
Limites:
Humans
Langue:
En
Journal:
Br J Radiol
/
Br. j. radiol
/
British journal of radiology
Année:
2024
Type de document:
Article
Pays d'affiliation:
Inde
Pays de publication:
Royaume-Uni