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Recent Advances in Photosensitizer Materials for Light-Mediated Tumor Therapy.
Chen, Minle; Zhu, Qianru; Zhang, Zhenzhen; Chen, Qiushui; Yang, Huanghao.
Affiliation
  • Chen M; New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350002, People's Republic of China.
  • Zhu Q; New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350002, People's Republic of China.
  • Zhang Z; New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350002, People's Republic of China.
  • Chen Q; New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350002, People's Republic of China.
  • Yang H; New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350002, People's Republic of China.
Chem Asian J ; 19(11): e202400268, 2024 Jun 03.
Article de En | MEDLINE | ID: mdl-38578217
ABSTRACT
Photodynamic therapy (PDT) as an emerging therapeutic method has drawn much attention in the treatment field for cancer. Photosensitizer, which can convert photon energy into cytotoxic species under light irradiation, is the core component in PDT. The design of photosensitizers still faces problems of light absorption, targeting, penetration and oxygen dependence. With the rapid progress of material science, various photosensitizers have been developed to produce cytotoxic species for treatment of tumor with high selectivity, safety, and noninvasiveness. Besides, the applications of photosensitizers have been expanded to diverse cancer treatments such as drug release, optogenetics and immune checkpoint blockade. In this review, we summarize the recent advances of photosensitizers in various therapeutic methods for cancer. Prevailing challenges and further prospects associated with photosensitizers are also discussed.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Photothérapie dynamique / Photosensibilisants / Tumeurs Limites: Animals / Humans Langue: En Journal: Chem Asian J Année: 2024 Type de document: Article Pays de publication: Allemagne

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Photothérapie dynamique / Photosensibilisants / Tumeurs Limites: Animals / Humans Langue: En Journal: Chem Asian J Année: 2024 Type de document: Article Pays de publication: Allemagne