Pyrrolizidine alkaloids and tropane alkaloids in milk samples from individual dairy farms of the German federal states of Bavaria and Schleswig-Holstein.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
; 41(6): 629-647, 2024 Jun.
Article
de En
| MEDLINE
| ID: mdl-38592240
ABSTRACT
1,2-Dehydro-pyrrolizidine alkaloids (PA), their corresponding N-oxides (PANO) and tropane alkaloids (TA), are toxic plant metabolites. If plant material, containing these toxins, is present in the feed of dairy cows these toxins can be transferred into milk. Here, milk was sampled directly from dairy farms in the German federal states of Bavaria and Schleswig-Holstein in 2020-2022 in order to investigate a possible contamination of milk at the production stage. In total, 228 milk samples were analysed for 54 PA/PANO and two TA by a sensitive LC-ESI-MS/MS method. In addition, a subset of milk samples (n = 85) was independently analysed for TA by a cooperating laboratory for verification. PA/PANO were found in 26 samples (11%) with a low median sum content of the contaminated samples of 0.024 µg/L. The highest level of contamination was 5.6 µg/L. Senecionine-, lycopsamine- and heliotrine-type PA/PANO were detected. In four samples (1.8%), atropine was determined up to 0.066 µg/L. The toxin levels in the milk samples hardly contributed to the total daily exposure. These data are first-time results on contamination rates and levels occurring in milk from individual dairy farms, based on a large sample number.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Alcaloïdes de type pyrrolizidine
/
Tropanes
/
Contamination des aliments
/
Lait
Limites:
Animals
Pays/Région comme sujet:
Europa
Langue:
En
Journal:
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
/
Food addit. contam. , Part A, Chem. anal. control expo. risk assess. (Print)
/
Food additives & contaminants. Part A. Chemistry, analysis, control, exposure & risk assessment (Online)
Sujet du journal:
CIENCIAS DA NUTRICAO
Année:
2024
Type de document:
Article
Pays d'affiliation:
Allemagne
Pays de publication:
Royaume-Uni