Clinical study on the pattern of lower-level lymphatic metastasis in primary tongue squamous cell carcinoma.
Hua Xi Kou Qiang Yi Xue Za Zhi
; 40(4): 422-427, 2022 Jul 25.
Article
de En, Zh
| MEDLINE
| ID: mdl-38596958
ABSTRACT
OBJECTIVES:
To study and analyze the clinical patterns of lower-level lymph node (â £ and â ¤) metastasis in primary tongue squamous cell carcinoma, and establish a reference for the decision-making of the lower-level neck dissection in tongue squamous cell carcinoma.METHODS:
A total of 203 patients with primary tongue squamous cell carcinoma were recruited. These patients underwent simultaneous/secondary comprehensive neck (level â -â ¤) dissection in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from January 2010 to December 2015. Their clinicopathological and follow-up data were obtained and analyzed to reveal the prognosis and risk factors of primary tongue squamous cell carcinoma with lower-level lymph node metastasis.RESULTS:
Among the 203 patients, the metastasis rates of levels â £ and â ¤ are 14.78% and 4.93%, respectively. Level â £ metastasis is more prevalent in males than females (P=0.04); non-smokers are more likely to have level â ¤ metastasis than smokers (P=0.046). Lymph node status in levels â ¢ and â £ are significantly associated with the risk of metastasis in level â ¤ (P=0.001). Patients with extracapsular invasion in level â ¢ have a significantly increased risk of metastasis in levels â £ (P=0.014) and â ¤ (P=0.026). The 5-year survival rate of patients with lower lymph node (â £/â ¤) metastasis is only 14.70%, which is an independent poor prognostic factor for patients with primary tongue squamous cell carcinoma (P<0.000 1).CONCLUSIONS:
Most primary tongue squamous cell carcinoma metastases occur in levels â -â ¢. However, the rate of lower-level lymph node metastasis is rather low. For the cN0 and cN+ patients with levels â -â ¡ lymph node metastases without extracapsular invasion, the strategy for level â ¤ management may be observation rather than dissection.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
/
Zh
Journal:
Hua Xi Kou Qiang Yi Xue Za Zhi
Sujet du journal:
ODONTOLOGIA
Année:
2022
Type de document:
Article
Pays d'affiliation:
Chine
Pays de publication:
Chine