Isolated Hydronephrosis and Urinary Tract Infection by Two Years of Age: A Population-Based Study.
J Pediatr
; 271: 114055, 2024 Aug.
Article
de En
| MEDLINE
| ID: mdl-38614256
ABSTRACT
OBJECTIVE:
To evaluate the risk for urinary tract infection (UTI) in infants with isolated hydronephrosis (IH). STUDYDESIGN:
A retrospective, population-based study including all infants insured by Clalit Health Services and followed from birth to age 2 years in 3 regions of central Israel. Infants were divided into 3 groups based on electronic medical record diagnoses by age 6 months (1) control no urological diagnosis; (2) IH; and (3) complicated urological diagnosis (CUD) any additional nephrological/urological diagnosis with/without HN. The primary outcome was a diagnosis of UTI in the first 2 years of life.RESULTS:
The cohort included 340â619 infants (52% male) 333â920 controls, 4369 with IH, and 2331 with CUD. Infants with IH were associated with a greater risk for UTI than control patients (17% vs 4%, P < .001). UTI risk for a male infant with IH was greater than for a female infant in the control group (12.6% vs 6.5%, P < .001). In a multivariable logistic regression analysis, both IH (OR 7.04; 95% CI 6.46-7.66) and CUD (OR 14.9; 95% CI 13.6-16.4) were independently associated with UTI.CONCLUSION:
Infants with IH are at a greater risk for UTI in the first 2 years of life, supporting the recommendation for a high index of suspicion for UTI in this population.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Infections urinaires
/
Hydronéphrose
Limites:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Pays/Région comme sujet:
Asia
Langue:
En
Journal:
J Pediatr
/
J. pediatr. (Rio J.)
/
Jornal de pediatria (Impresso)
Année:
2024
Type de document:
Article
Pays de publication:
États-Unis d'Amérique