A rare case of methemoglobinemia in a preterm newborn with unclear etiology.
J Neonatal Perinatal Med
; 17(2): 261-264, 2024.
Article
de En
| MEDLINE
| ID: mdl-38640175
ABSTRACT
Cyanosis is a bluish discoloration of the tissues due to increased levels of deoxygenated hemoglobin in capillaries. It is a common finding in newborn infants that can be caused by different diseases, including pulmonary, cardiac, infectious, and hematological disorders. Methemoglobinemia is a rare cause of cyanosis, in which hemoglobin is oxidized, changing its heme iron configuration from the ferrous (Fe2 +) to the ferric (Fe3 +) state, creating methemoglobin (Met-Hb), a form that does not bind oxygen, leading to decreased oxygen delivery to the tissues and cyanosis. We report a rare case of a preterm newborn, who developed cyanosis and worsening hypoxemia on day ten of life, she was found to have elevated Met-Hb percentage in blood gas analysis that required treatment with intravenous methylene blue. Her symptoms resolved after a period of maintenance treatment with oral methylene blue and ascorbic acid, and the etiology of her disease remains unclear.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Acide ascorbique
/
Prématuré
/
Cyanose
/
Méthémoglobinémie
/
Bleu de méthylène
Limites:
Female
/
Humans
/
Newborn
Langue:
En
Journal:
J Neonatal Perinatal Med
Année:
2024
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique