Macrophage niche imprinting as a determinant of macrophage identity and function.
Cell Immunol
; 399-400: 104825, 2024.
Article
de En
| MEDLINE
| ID: mdl-38648700
ABSTRACT
Macrophage niches are the anatomical locations within organs or tissues consisting of various cells, intercellular and extracellular matrix, transcription factors, and signaling molecules that interact to influence macrophage self-maintenance, phenotype, and behavior. The niche, besides physically supporting macrophages, imposes a tissue- and organ-specific identity on the residing and infiltrating monocytes and macrophages. In this review, we give examples of macrophage niches and the modes of communication between macrophages and surrounding cells. We also describe how macrophages, acting against their immune defensive nature, can create a hospitable niche for pathogens and cancer cells.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Macrophages
Limites:
Animals
/
Humans
Langue:
En
Journal:
Cell Immunol
/
Cell. immunol
/
Cellular immunology
Année:
2024
Type de document:
Article
Pays de publication:
Pays-Bas