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Biomedical and Biotechnological Potential of Animal Venoms: Bothrops Snake Venoms and their Antimicrobial Applications.
Reimann, Raissa; Barreto, Breno; Romano, Filippo; Medeiros, Jade; Camargo, Bruna C; N da Silva, Josiel; Soares, Ana Luiza B; F de Souza, Mateus; Macedo, Jamile M; Kayano, Anderson M; Zuliani, Juliana P; N de Oliveira, Ana; L da Silva, Saulo; Diniz-Sousa, Rafaela; Soares, Andreimar M.
Affiliation
  • Reimann R; Curso de Medicina, Centro Universitário São Lucas, SÃO LUCAS PVH, Porto Velho-RO, Brazil.
  • Barreto B; Curso de Medicina, Centro Universitário São Lucas, SÃO LUCAS PVH, Porto Velho-RO, Brazil.
  • Romano F; Curso de Medicina, Centro Universitário São Lucas, SÃO LUCAS PVH, Porto Velho-RO, Brazil.
  • Medeiros J; Curso de Medicina, Centro Universitário São Lucas, SÃO LUCAS PVH, Porto Velho-RO, Brazil.
  • Camargo BC; Curso de Medicina, Centro Universitário São Lucas, SÃO LUCAS PVH, Porto Velho-RO, Brazil.
  • N da Silva J; Curso de Medicina, Centro Universitário São Lucas, SÃO LUCAS PVH, Porto Velho-RO, Brazil.
  • Soares ALB; Curso de Medicina, Centro Universitário São Lucas, SÃO LUCAS PVH, Porto Velho-RO, Brazil.
  • F de Souza M; Fundação Oswaldo Cruz, FIOCRUZ, Fiocruz Rondônia, Porto Velho-RO, Brazil.
  • Macedo JM; Rede de Pesquisa e Conhecimento de Excelência na Amazônia Ocidental, RED-CONEXAO, Brazil.
  • Kayano AM; Fundação Oswaldo Cruz, FIOCRUZ, Fiocruz Rondônia, Porto Velho-RO, Brazil.
  • Zuliani JP; Rede de Pesquisa e Conhecimento de Excelência na Amazônia Ocidental, RED-CONEXAO, Brazil.
  • N de Oliveira A; Fundação Oswaldo Cruz, FIOCRUZ, Fiocruz Rondônia, Porto Velho-RO, Brazil.
  • L da Silva S; Rede de Pesquisa e Conhecimento de Excelência na Amazônia Ocidental, RED-CONEXAO, Brazil.
  • Diniz-Sousa R; Centro de Medicina Tropical, CEPEM, SESAU-RO, Porto Velho-RO, Brazil.
  • Soares AM; Rede de Pesquisa e Conhecimento de Excelência na Amazônia Ocidental, RED-CONEXAO, Brazil.
Curr Med Chem ; 2024 Apr 26.
Article de En | MEDLINE | ID: mdl-38676530
ABSTRACT
The pursuit of novel treatment alternatives to address the accumulated resistance to antimicrobials over the years has prompted the scientific community to explore biodiversity, particularly animal venom, as a potential source of new antimicrobial drugs. Snake venoms, with their complex mixtures of components, are particularly promising targets for investigation in this regard. The search for novel molecules exhibiting antimicrobial activity against multidrug-resistant strains is of paramount importance for public health and numerous research groups worldwide. High expectations within the healthcare field are supported by the scientific literature, which highlights the potential development of innovative drugs through in vivo and in vitro application, depending on dose titration. Snake venoms and their molecules and peptides offer exponential possibilities for biotechnological applications as antimicrobial agents. However, many uncertainties and unexplored avenues remain, presenting opportunities for discoveries and research.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Curr Med Chem Sujet du journal: QUIMICA Année: 2024 Type de document: Article Pays d'affiliation: Brésil Pays de publication: Émirats arabes unis

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Curr Med Chem Sujet du journal: QUIMICA Année: 2024 Type de document: Article Pays d'affiliation: Brésil Pays de publication: Émirats arabes unis