Applied physiology: gut microbiota and antimicrobial therapy.
Eur J Appl Physiol
; 124(6): 1631-1643, 2024 Jun.
Article
de En
| MEDLINE
| ID: mdl-38683402
ABSTRACT
The gut microbiota plays an important role in maintaining human health and in the pathogenesis of several diseases. Antibiotics are among the most commonly prescribed drugs and have a significant impact on the structure and function of the gut microbiota. The understanding that a healthy gut microbiota prevents the development of many diseases has also led to its consideration as a potential therapeutic target. At the same time, any factor that alters the gut microbiota becomes important in this approach. Exercise and antibacterial therapy have a direct effect on the microbiota. The review reflects the current state of publications on the mechanisms of intestinal bacterial involvement in the pathogenesis of cardiovascular, metabolic, and neurodegenerative diseases. The physiological mechanisms of the influence of physical activity on the composition of the gut microbiota are considered. The mechanisms of the common interface between exercise and antibacterial therapy will be considered using the example of several socially important diseases. The aim of the study is to show the physiological relationship between the effects of exercise and antibiotics on the gut microbiota.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Exercice physique
/
Microbiome gastro-intestinal
/
Antibactériens
Limites:
Animals
/
Humans
Langue:
En
Journal:
Eur J Appl Physiol
/
Eur. j. appl. physiol
/
European journal of applied physiology
Sujet du journal:
FISIOLOGIA
Année:
2024
Type de document:
Article
Pays d'affiliation:
Russie
Pays de publication:
Allemagne