The multifaceted role of the mineralocorticoid receptor in cancers.
J Steroid Biochem Mol Biol
; 242: 106541, 2024 09.
Article
de En
| MEDLINE
| ID: mdl-38714226
ABSTRACT
The mineralocorticoid receptor (MR/NR3C2) is a member of the family of steroid receptors (SR) which also includes the estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR) and glucocorticoid receptor (GR). They function primarily as nuclear receptors to regulate gene expression. While the other steroid hormone receptors are known to play important roles in the pathogenesis and progression of many cancers, relatively little is understood about the role of MR in cancer biology. This review focuses on examining new insights into the potential roles and mechanisms of action of MR in cancers.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Récepteurs des minéralocorticoïdes
/
Tumeurs
Limites:
Animals
/
Humans
Langue:
En
Journal:
J Steroid Biochem Mol Biol
Sujet du journal:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
Année:
2024
Type de document:
Article
Pays de publication:
Royaume-Uni