[Autoimmune Autonomic Ganglionopathy and Acute Autonomic Sensory Neuropathy].
Brain Nerve
; 76(5): 562-568, 2024 May.
Article
de Ja
| MEDLINE
| ID: mdl-38741497
ABSTRACT
Autoimmune autonomic ganglionopathy (AAG) and acute autonomic sensory neuropathy (AASN) are immune-mediated neuropathies that affect the autonomic and/or dorsal root ganglia. Autoantibodies against the nicotinic ganglionic acetylcholine receptor (gAChR) detected in the sera of patients with AAG play a key role in the pathogenesis of this condition. Notably, gAChR antibodies are not detected in the sera of patients with AASN. Currently, AAG and AASN are not considered to be on the same spectrum with regard to disease concept based on clinical symptoms and laboratory findings. However, extra-autonomic brain symptoms (including psychiatric symptoms and personality changes) and endocrine disorders occur in both diseases, which suggests shared pathophysiology between the two conditions.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Autoanticorps
/
Maladies du système nerveux autonome
/
Ganglions du système nerveux autonome
Limites:
Humans
Langue:
Ja
Journal:
Brain Nerve
Sujet du journal:
CEREBRO
/
NEUROLOGIA
Année:
2024
Type de document:
Article