Genetic surveillance of insecticide resistance in African Anopheles populations to inform malaria vector control.
Trends Parasitol
; 40(7): 604-618, 2024 Jul.
Article
de En
| MEDLINE
| ID: mdl-38760258
ABSTRACT
Insecticide resistance in malaria vector populations poses a major threat to malaria control, which relies largely on insecticidal interventions. Contemporary vector-control strategies focus on combatting resistance using multiple insecticides with differing modes of action within the mosquito. However, diverse genetic resistance mechanisms are present in vector populations, and continue to evolve. Knowledge of the spatial distribution of these genetic mechanisms, and how they impact the efficacy of different insecticidal products, is critical to inform intervention deployment decisions. We developed a catalogue of genetic-resistance mechanisms in African malaria vectors that could guide molecular surveillance. We highlight situations where intervention deployment has led to resistance evolution and spread, and identify challenges in understanding and mitigating the epidemiological impacts of resistance.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Résistance aux insecticides
/
Lutte contre les moustiques
/
Vecteurs moustiques
/
Insecticides
/
Paludisme
/
Anopheles
Limites:
Animals
Pays/Région comme sujet:
Africa
Langue:
En
Journal:
Trends Parasitol
Sujet du journal:
PARASITOLOGIA
Année:
2024
Type de document:
Article