Revisiting the advances and challenges in the clinical applications of extracellular vesicles in cancer.
Cancer Lett
; 593: 216960, 2024 Jul 01.
Article
de En
| MEDLINE
| ID: mdl-38762194
ABSTRACT
Extracellular vesicles (EVs) have been the subject of an exponentially growing number of studies covering their biogenesis mechanisms, isolation and analysis techniques, physiological and pathological roles, and clinical applications, such as biomarker and therapeutic uses. Nevertheless, the heterogeneity of EVs both challenges our understanding of them and presents new opportunities for their potential application. Recently, the EV field experienced a wide range of advances. However, the challenges also remain huge. This review focuses on the recent progress and difficulties encountered in the practical use of EVs in clinical settings. In addition, we also explored the concept of EV heterogeneity to acquire a more thorough understanding of EVs and their involvement in cancer, specifically focusing on the fundamental nature of EVs.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Marqueurs biologiques tumoraux
/
Vésicules extracellulaires
/
Tumeurs
Limites:
Animals
/
Humans
Langue:
En
Journal:
Cancer Lett
Année:
2024
Type de document:
Article
Pays d'affiliation:
Chine