Electrochemical quinuclidine-mediated Minisci-type acylation of N-heterocycles with aldehydes.

Li, Yongmei; Sun, Liangbo; Huang, Shengyang; Xu, Kun; Zeng, Cheng-Chu

Li, Yongmei; Sun, Liangbo; Huang, Shengyang; Xu, Kun; Zeng, Cheng-Chu.

Affiliation

Li Y; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China. kunxu@bjut.edu.cn.
Sun L; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China. kunxu@bjut.edu.cn.
Huang S; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China. kunxu@bjut.edu.cn.
Xu K; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China. kunxu@bjut.edu.cn.
Zeng CC; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China. kunxu@bjut.edu.cn.

Chem Commun (Camb) ; 60(48): 6174-6177, 2024 Jun 11.

Article de En | MEDLINE | ID: mdl-38804811

ABSTRACT

ABSTRACT

The electro-generation of acyl radicals from both aromatic and aliphatic aldehydes remains an unmet challenge. We provide a solution to this challenge by merging electro-oxidation and a quinuclidine-mediated hydrogen atom transfer strategy. The generation of acyl radicals at decreased applied potentials compared to that of formyl oxidation exhibits excellent functional group compatibility.

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Chem Commun (Camb) Sujet du journal: QUIMICA Année: 2024 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google