Advances in the Study of Etiology and Molecular Mechanisms of Sensorineural Hearing Loss.
Cell Biochem Biophys
; 2024 Jun 07.
Article
de En
| MEDLINE
| ID: mdl-38849694
ABSTRACT
Sensorineural hearing loss (SNHL), a multifactorial progressive disorder, results from a complex interplay of genetic and environmental factors, with its underlying mechanisms remaining unclear. Several pathological factors are believed to contribute to SNHL, including genetic factors, ion homeostasis, cell apoptosis, immune inflammatory responses, oxidative stress, hormones, metabolic syndrome, human cytomegalovirus infection, mitochondrial damage, and impaired autophagy. These factors collectively interact and play significant roles in the onset and progression of SNHL. The present review offers a comprehensive overview of the various factors that contribute to SNHL, emphasizes recent developments in understanding its etiology, and explores relevant preventive and intervention measures.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
Cell Biochem Biophys
Sujet du journal:
BIOFISICA
/
BIOQUIMICA
Année:
2024
Type de document:
Article
Pays d'affiliation:
Chine