On-mask detection of SARS-CoV-2 related substances by surface enhanced Raman scattering.
Talanta
; 277: 126403, 2024 Sep 01.
Article
de En
| MEDLINE
| ID: mdl-38878511
ABSTRACT
We have developed a convenient surface-enhanced Raman scattering (SERS) platform based on vertical standing gold nanowires (v-AuNWs) which enabled the on-mask detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) related substances such as the Spike-1 protein and the corresponding pseudo-virus. The Spike-1 protein was clearly distinguished from BSA protein with an accuracy above 99 %, and the detection limit could be achieved down to 0.01 µg/mL. Notably, a similar accuracy was achieved for the pseudo-SARS-CoV-2 (pSARS-2) virus as compared to the pseudo-influenza H7N9 (pH7N9) virus. The sensing strategy and setups could be easily adapted to the real SARS-CoV-2 virus and other highly contagious viruses. It provided a promising way to screen the virus carriers by a fast evaluation of their wearing v-AuNWs integrated face-mask which was mandatory during the pandemic.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Analyse spectrale Raman
/
SARS-CoV-2
/
COVID-19
/
Or
/
Masques
Limites:
Humans
Langue:
En
Journal:
Talanta
Année:
2024
Type de document:
Article
Pays d'affiliation:
Chine