No add-on therapeutic benefit of at-home anodal tDCS of the primary motor cortex to mindfulness meditation in patients with fibromyalgia.
Clin Neurophysiol
; 164: 168-179, 2024 Aug.
Article
de En
| MEDLINE
| ID: mdl-38901112
ABSTRACT
OBJECTIVE:
This study investigated the efficacy of combining at-home anodal transcranial direct current stimulation (tDCS) of the left primary motor cortex (M1) with mindfulness meditation (MM) in fibromyalgia patients trained in mindfulness.METHODS:
Thirty-seven patients were allocated to receive ten daily sessions of MM paired with either anodal or sham tDCS over the primary motor cortex. Primary outcomes were pain intensity and quality of life. Secondary outcomes were psychological impairment, sleep quality, mood, affective pain, mindfulness level, and transcranial magnetic stimulation (TMS) measures of cortical excitability. Outcomes were analyzed pre- and post-treatment, with a one-month follow-up.RESULTS:
We found post-tDCS improvement in all clinical outcomes, including mindfulness level, except for positive affect and stress, in both groups without significant difference between active and sham conditions. No significant group*time interaction was found for all clinical and TMS outcomes.CONCLUSIONS:
Our findings demonstrate no synergistic or add-on efffect of anodal tDCS of the left M1 compared to the proper effect of MM in patients with fibromyalgia.SIGNIFICANCE:
Our findings challenge the potential of combining anodal tDCS of the left M1 and MM in fibromyalgia.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Fibromyalgie
/
Méditation
/
Pleine conscience
/
Stimulation transcrânienne par courant continu
/
Cortex moteur
Limites:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Clin Neurophysiol
Sujet du journal:
NEUROLOGIA
/
PSICOFISIOLOGIA
Année:
2024
Type de document:
Article
Pays de publication:
Pays-Bas