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Black seed assisted synthesis, characterization, free radical scavenging, antimicrobial and anti-inflammatory activity of iron oxide nanoparticles.
Shanmugam, Rajeshkumar; Tharani, M; Abullais, Shahabe Saquib; Patil, Santosh R; Karobari, Mohmed Isaqali.
Affiliation
  • Shanmugam R; Nanobiomedicine Lab, Centre for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 602105, India.
  • Tharani M; Nanobiomedicine Lab, Centre for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 602105, India.
  • Abullais SS; Department of Periodontics, College of Dentistry, King Khalid University, Abha, 62529, Saudi Arabia.
  • Patil SR; Department of Oral Medicine and Radiology, Chhattisgarh Dental College & Research Institute, Chhattisgarh, India.
  • Karobari MI; Department of Dental Research, Center for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 602105, India.
BMC Complement Med Ther ; 24(1): 241, 2024 Jun 20.
Article de En | MEDLINE | ID: mdl-38902620
ABSTRACT
Iron nanoparticles comprise a significant class of inorganic nanoparticles, which discover applications in various zones by prudence of their few exciting properties. This study achieved the green synthesis of iron oxide nanoparticles (IONPs) by black cumin seed (Nigella sativa) extract, which acts as a reducing and capping agent. The iron nanoparticles and black cumin extract were synthesized in three different concentrations (0101, 0204,0104). UV-visible spectroscopy, XRD, FTIR, and AFM characterized the synthesized iron oxide nanoparticles. UV-visible spectra show the maximum absorbance peak of 0101 concentration at 380 nm. The other concentrations, such as 0204, peaked at 400 nm and 0104 at 680 nm, confirming the formation of iron oxide nanoparticles. AFM analysis reveals the spherical shape of iron oxide nanoparticles. The XRD spectra reveal the (fcc) cubic crystal structure of the iron oxide nanoparticles. The FTIR analysis's peaks at 457.13, 455.20, and 457.13 cm-1 depict the characteristic iron nanoparticle synthesis. The black cumin extract-mediated iron oxide nanoparticles show substantial antibacterial, antifungal, antioxidant and anti-inflammatory activity in a dose-dependent manner.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Graines / Extraits de plantes / Nigella sativa / Anti-infectieux / Anti-inflammatoires Langue: En Journal: BMC Complement Med Ther Année: 2024 Type de document: Article Pays d'affiliation: Inde Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Graines / Extraits de plantes / Nigella sativa / Anti-infectieux / Anti-inflammatoires Langue: En Journal: BMC Complement Med Ther Année: 2024 Type de document: Article Pays d'affiliation: Inde Pays de publication: Royaume-Uni