The European psychiatric association (EPA) - early career psychiatrists committee survey on trainees' and early-career psychiatrists' attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment.
World J Biol Psychiatry
; 25(6): 342-351, 2024 Jul.
Article
de En
| MEDLINE
| ID: mdl-38905131
ABSTRACT
OBJECTIVES:
This survey assessed psychiatry residents'/early-career psychiatrists' attitudes towards the utility of therapeutic drug monitoring (TDM) of antipsychotics.METHODS:
A previously developed questionnaire on attitudes on TDM utility during antipsychotic treatment was cross-sectionally disseminated by national coordinators between 01/01/2022-31/12/2023. The frequency of using TDM for antipsychotics other than clozapine was the main outcome in a linear regression analysis, including sex, clinical setting, caseload, and factors generated by an exploratory factor analysis. Comparisons between residents and early-career psychiatrists, respondents working in in- and outpatient settings, and low-/middle- and high-income countries were performed.RESULTS:
Altogether, 1,237 respondents completed the survey, with 37.9% having never used TDM for antipsychotics. Seven factors explained 41% of response variance; six of them were associated with frequency of TDM use (p < 0.05). Items with highest loadings for factors included clinical benefits of TDM (factors A and E 0.7), negative expectations for beliefs of patients towards TDM (factor B 0.6-0.7), weak TDM scientific evidence (factor C 0.8), and TDM availability (factor D -0.8). Respondents from low-/middle-income countries were less likely to frequently/almost always use TDM compared to high-income countries (9.4% vs. 21.5%, p < 0.001).DISCUSSION:
TDM use for antipsychotics was poor and associated with limited knowledge and insufficient availability.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Psychiatrie
/
Neuroleptiques
/
Attitude du personnel soignant
/
Surveillance des médicaments
Limites:
Adult
/
Female
/
Humans
/
Male
Pays/Région comme sujet:
Europa
Langue:
En
Journal:
World J Biol Psychiatry
Sujet du journal:
PSIQUIATRIA
Année:
2024
Type de document:
Article
Pays d'affiliation:
Suisse