DNA break induces rapid transcription repression mediated by proteasome-dependent RNAPII removal.

He, Shuaixin; Huang, Zhiyuan; Liu, Yang; Ha, Taekjip; Wu, Bin

He, Shuaixin; Huang, Zhiyuan; Liu, Yang; Ha, Taekjip; Wu, Bin.

Affiliation

He S; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Huang Z; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Liu Y; Department of Biochemistry, The University of Utah, Salt Lake City, UT 84112, USA.
Ha T; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Wu B; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The Solomon H Snyder Department of Neuroscience, Johns Hopkins University Sc

Cell Rep ; 43(7): 114420, 2024 Jul 23.

Article de En | MEDLINE | ID: mdl-38954517

Sujet(s)
Mots clés

CP: Molecular biology; CRISPR-Cas9; DNA damage repair; proteasome; single molecule; transcription

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Transcription génétique / RNA polymerase II / Proteasome endopeptidase complex / Cassures double-brin de l'ADN Limites: Humans Langue: En Journal: Cell Rep Année: 2024 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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