A novel fluorescent probe with a phosphofluorene molecular structure for selective detection of hydrogen sulfide in living cells.
RSC Adv
; 14(29): 20966-20973, 2024 Jun 27.
Article
de En
| MEDLINE
| ID: mdl-38957581
ABSTRACT
Hydrogen sulfide (H2S) gas plays a significant role in biological regulation. With advancements in technology, H2S has been discovered across diverse fields, necessitating a comprehensive understanding of its physiological functions through monitoring changes in H2S within complex environments and physiological processes. In this study, we designed a phosphofluorene-based conjugate probe PPF-CDNB with an asymmetric π-conjugated phosphine structure and utilized dinitrophenyl ether as the recognition site for H2S. PPF-CDNB exhibited exceptional resistance to interference and demonstrated stability over a broad pH range (3.0-10.0), making it suitable for various environmental conditions. Intracellular experiments revealed that PPF-CDNB effectively monitored both endogenous and exogenous levels of H2S.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
RSC Adv
Année:
2024
Type de document:
Article
Pays de publication:
Royaume-Uni