Biofabrication of Living Actuators.
Annu Rev Biomed Eng
; 26(1): 223-245, 2024 Jul.
Article
de En
| MEDLINE
| ID: mdl-38959387
ABSTRACT
The impact of tissue engineering has extended beyond a traditional focus in medicine to the rapidly growing realm of biohybrid robotics. Leveraging living actuators as functional components in machines has been a central focus of this field, generating a range of compelling demonstrations of robots capable of muscle-powered swimming, walking, pumping, gripping, and even computation. In this review, we highlight key advances in fabricating tissue-scale cardiac and skeletal muscle actuators for a range of functional applications. We discuss areas for future growth including scalable manufacturing, integrated feedback control, and predictive modeling and also propose methods for ensuring inclusive and bioethics-focused pedagogy in this emerging discipline. We hope this review motivates the next generation of biomedical engineers to advance rational design and practical use of living machines for applications ranging from telesurgery to manufacturing to on- and off-world exploration.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Robotique
/
Muscles squelettiques
/
Ingénierie tissulaire
Limites:
Animals
/
Humans
Langue:
En
Journal:
Annu Rev Biomed Eng
Sujet du journal:
ENGENHARIA BIOMEDICA
Année:
2024
Type de document:
Article