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Safety and pharmacokinetics of subcutaneous administration of broadly neutralizing anti-HIV-1 monoclonal antibodies (bNAbs), given to HIV-1 exposed, uninfected neonates and infants: study protocol for a phase I trial.
Goga, Ameena; Ramraj, Trisha; Naidoo, Logashvari; Daniels, Brodie; Matlou, Masefetsane; Chetty, Terusha; Dassaye, Reshmi; Ngandu, Nobubelo K; Galli, Laura; Reddy, Tarylee; Seocharan, Ishen; Ndlangamandla, Qondeni; September, Qholokazi; Ngcobo, Nokwanda; Reddy, Mayuri; Cafun-Naidoo, Tamon; Woeber, Kubashni; Jeenarain, Nitesha; Imamdin, Rabia; Maharajh, Keshnee; Ramjeth, Ashmintha; Bhengu, Thobile; Clarence, Emma; Van de Perre, Philippe; Tylleskär, Thorkild; Nagot, Nicolas; Moles, Jean-Pierre; Moore, Penny L; Mkhize, Nonhlanhla N; Gama, Lucio; Dispinseri, Stefania; Biswas, Priscilla; Scarlatti, Gabriella.
Affiliation
  • Goga A; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Ramraj T; Department of Paediatrics and Child Health, University of Pretoria, Pretoria, South Africa.
  • Naidoo L; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Daniels B; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Matlou M; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Chetty T; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Dassaye R; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Ngandu NK; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Galli L; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Reddy T; Viral Evolution and Transmission Unit, IRCCS Ospedale San Raffaele s.r.l., Milan, Italy.
  • Seocharan I; Biostatistics Research Unit, South African Medical Research Council, Durban, South Africa.
  • Ndlangamandla Q; Biostatistics Research Unit, South African Medical Research Council, Durban, South Africa.
  • September Q; Biostatistics Research Unit, South African Medical Research Council, Durban, South Africa.
  • Ngcobo N; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Reddy M; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Cafun-Naidoo T; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Woeber K; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Jeenarain N; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Imamdin R; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Maharajh K; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Ramjeth A; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Bhengu T; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Clarence E; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Van de Perre P; HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, South Africa.
  • Tylleskär T; Pathogenesis and Control of Chronic and Emerging Infections, University of Montpellier, INSERM, Etablissement Français du Sang; CHU Montpellier, Montpellier, France.
  • Nagot N; Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
  • Moles JP; Pathogenesis and Control of Chronic and Emerging Infections, University of Montpellier, INSERM, Etablissement Français du Sang; CHU Montpellier, Montpellier, France.
  • Moore PL; Pathogenesis and Control of Chronic and Emerging Infections, University of Montpellier, INSERM, Etablissement Français du Sang; CHU Montpellier, Montpellier, France.
  • Mkhize NN; SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Gama L; Center for HIV and STIs, National Institute for Communicable Diseases a Division of the National Health Laboratory Service, Johannesburg, South Africa.
  • Dispinseri S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Biswas P; SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Scarlatti G; Center for HIV and STIs, National Institute for Communicable Diseases a Division of the National Health Laboratory Service, Johannesburg, South Africa.
BMC Infect Dis ; 24(1): 712, 2024 Jul 20.
Article de En | MEDLINE | ID: mdl-39033300
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Anticorps anti-VIH / Infections à VIH / VIH-1 (Virus de l'Immunodéficience Humaine de type 1) Limites: Female / Humans / Infant / Male / Newborn Pays/Région comme sujet: Africa Langue: En Journal: BMC Infect Dis Sujet du journal: DOENCAS TRANSMISSIVEIS Année: 2024 Type de document: Article Pays d'affiliation: République d'Afrique du Sud Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Anticorps anti-VIH / Infections à VIH / VIH-1 (Virus de l'Immunodéficience Humaine de type 1) Limites: Female / Humans / Infant / Male / Newborn Pays/Région comme sujet: Africa Langue: En Journal: BMC Infect Dis Sujet du journal: DOENCAS TRANSMISSIVEIS Année: 2024 Type de document: Article Pays d'affiliation: République d'Afrique du Sud Pays de publication: Royaume-Uni