Analyzing venous thromboembolism risk in malignant tumors: thromboelastogram and coagulation factors study.
Biomark Med
; 18(8): 373-383, 2024.
Article
de En
| MEDLINE
| ID: mdl-39041842
ABSTRACT
Aim:
This retrospective clinical study was designed to examine the predictive value of thromboelastography (TEG) combined with coagulation function for venous thromboembolism (VTE) in hospitalized patients with cancer. Materials &methods:
Among 215 patients admitted between May 2020 and January 2022, 39 (18.14%) were diagnosed with VTE during hospitalization.Results:
Significant differences were found in D-dimer, ATIII and TEG parameters (maximum amplitude and coagulation index) between VTE-positive and VTE-negative patients (p < 0.05). Multivariate analysis revealed tumor node metastasis stage, concomitant infection, smoking history and D-dimer as independently associated with VTE. The constructed model and D-dimer areas under the curve were 0.809 and 0.764, respectively.Conclusion:
TEG parameters were not significantly predictive indicators for VTE, with D-dimer remaining a key predictor.
[Box see text].
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Thromboélastographie
/
Produits de dégradation de la fibrine et du fibrinogène
/
Thromboembolisme veineux
/
Tumeurs
Limites:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Biomark Med
Sujet du journal:
BIOQUIMICA
/
MEDICINA
Année:
2024
Type de document:
Article
Pays d'affiliation:
Chine