Significant pituitary siderosis is common in transfusion-dependent sickle cell disease.
Blood
; 144(13): 1457-1459, 2024 Sep 26.
Article
de En
| MEDLINE
| ID: mdl-39046820
ABSTRACT
ABSTRACT Chronically transfused patients with sickle cell disease typically do not exhibit iron-mediated extrahepatic toxicity. However, we demonstrate that the pituitary gland is vulnerable to iron deposition, and it occurs regardless of other extrahepatic involvement. Severe pituitary siderosis is associated with early organ dysfunction.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Sidérose
/
Drépanocytose
Limites:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Blood
Année:
2024
Type de document:
Article
Pays de publication:
États-Unis d'Amérique