Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis.
Future Cardiol
; 20(4): 221-228, 2024 Mar 11.
Article
de En
| MEDLINE
| ID: mdl-39049769
ABSTRACT
Aim:
We aim to analyze past literature to evaluate the efficacy of coenzyme Q10 (CoQ-10) in the population with heart failure (HF).Methods:
A systematic literature search was conducted through MEDLINE (via PubMed) and Cochrane Library. The outcomes analyzed were a reduction in HF-related mortality, an improvement in exercise capacity, and the left ventricular ejection fraction (LVEF).Results:
Among 16 studies, CoQ-10 significantly reduced HF-related mortality by 40% and improved exercise capacity in patients with HF, but demonstrated no significant difference in LVEF however, the potential of its efficacy on LVEF could not be ruled out.Conclusion:
CoQ-10 significantly enhances exercise capacity and reduces HF-related mortality; however, its impact on patients with reduced LVEF requires further investigation.
[Box see text].
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Ubiquinones
/
Défaillance cardiaque
Limites:
Humans
Langue:
En
Journal:
Future Cardiol
/
Future cardiol
/
Future cardiology
Sujet du journal:
CARDIOLOGIA
Année:
2024
Type de document:
Article
Pays d'affiliation:
Pakistan
Pays de publication:
Royaume-Uni