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Timely Shaver Treatment Removes Chronic Tophaceous Mass Improve Surgical Outcomes.
Yen, Patrick Szu-Ying; Tu, Hung-Pin; Huang, Shu-Hung; Lee, Su-Shin.
Affiliation
  • Yen PS; School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Tu HP; Department of Public Health and Environmental Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Taiwan.
  • Huang SH; Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
  • Lee SS; Regenerative medicine and cell therapy research center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Int J Med Sci ; 21(10): 1799-1805, 2024.
Article de En | MEDLINE | ID: mdl-39113890
ABSTRACT

Background:

Current treatments with urate-lowering therapy (ULT) are effective for most patients with gout. However, approximately 10% of these patients do not respond well to ULT and develop chronic tophus lesions.

Objective:

This study aimed to evaluate the efficacy of surgery involving the shaver technique against chronic tophus lesions.

Methods:

This single-center, retrospective cohort study included 217 patients who had cumulatively undergone 303 shaver-assisted procedures between 2002 and 2018. Surgical outcomes were assessed in terms of the length of hospital stay (LOS) and wound healing time.

Results:

LOS and wound healing time were longer in patients with a preoperative tophus infection and lower extremity lesions than in those without infection and with upper extremity lesions (respectively, LOS 12.7 vs. 8.6 days; wound healing time 22.7 vs. 16.3 days). However, factors such as age, sex, body mass index, renal function, or uricemia level exerted no significant effect on surgical outcomes.

Conclusion:

Surgery involving the shaver technique should be performed before tophus infection. Clinical outcomes tend to be better for upper extremity lesions than for lower extremity lesions.
Sujet(s)
Mots clés

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cicatrisation de plaie / Goutte / Durée du séjour Limites: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Langue: En Journal: Int J Med Sci Sujet du journal: MEDICINA Année: 2024 Type de document: Article Pays d'affiliation: Taïwan Pays de publication: Australie

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cicatrisation de plaie / Goutte / Durée du séjour Limites: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Langue: En Journal: Int J Med Sci Sujet du journal: MEDICINA Année: 2024 Type de document: Article Pays d'affiliation: Taïwan Pays de publication: Australie