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Role of Recombinant Proteins for Treating Rheumatoid Arthritis.
Soleimani Sasani, Mahboubeh; Moradi, Yeganeh.
Affiliation
  • Soleimani Sasani M; Shahid Beheshti University, Tehran, Iran.
  • Moradi Y; Department of Biotechnology Engineering, Faculty of Medical Engineering, Shahab Danesh University, Qom, Iran.
Avicenna J Med Biotechnol ; 16(3): 137-145, 2024.
Article de En | MEDLINE | ID: mdl-39132628
ABSTRACT
Rheumatoid Arthritis (RA) is an autoimmune disease and chronic inflammatory disorder that affects joints and causes inflammation, pain, stiffness, and eventually progressive joint destruction. Approximately 1% of the world's population is estimated to suffer from RA, and if this disease is left untreated, it can lead to severe disability. Despite all the efforts and advances made by professionals in the field, there is currently no definitive treatment for RA, and most treatment strategies are aimed at relieving symptoms and improving patients' quality of life. One of the most promising current approaches is the use of recombinant proteins that target specific signaling pathways involved in the development of RA to alleviate symptoms and slow the progression of the disease. This article discusses the genetic and immunological factors that influence the development of RA, recombinant proteins, methods of using these proteins, approved drugs, and side effects associated with treating RA.
Mots clés

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Avicenna J Med Biotechnol Année: 2024 Type de document: Article Pays d'affiliation: Iran Pays de publication: Iran

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Avicenna J Med Biotechnol Année: 2024 Type de document: Article Pays d'affiliation: Iran Pays de publication: Iran