Copper clearance in a subgroup of patients with chorea.
Biol Psychiatry
; 19(12): 1677-84, 1984 Dec.
Article
de En
| MEDLINE
| ID: mdl-6518216
ABSTRACT
Rat studies recently have suggested that the corpus striatum appears to be selectively and markedly affected by copper deficiencies beginning in the post-weanling period. A study of copper clearances has revealed that four out of five patients with chorea have depressed clearances between 0.00674 and .00313 (reference range 0.0137-0.0404 cc/min). The patients with depressed copper clearances had psychiatric illness themselves or in first-degree relatives. In the case of one patient, copper supplementation resulted in an abatement of symptoms that reversed on a single-blind crossover.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Chorée
/
Cuivre
Type d'étude:
Clinical_trials
Limites:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Biol Psychiatry
Année:
1984
Type de document:
Article