Effect of pyridoxal administration on the contents of pyridoxal phosphate and gamma-aminobutyric acid in mouse brain.
J Nutr Sci Vitaminol (Tokyo)
; 24(3): 255-62, 1978.
Article
de En
| MEDLINE
| ID: mdl-690726
ABSTRACT
Many mice treated with a high single dose of PL died in convulsions. The convulsions were very similar to those induced with some anti B6 in several ways (1) a long latent period occurs betfore convulsions; (2) PLP levels in brain decrease; (3) GABA levels in brain, especially in synaptosomal fraction, decrease. The possibility that a deranged GABA metabolism in nerve ending may be a major cause of the convulsions is discussed.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Pyridoxal
/
Phosphate de pyridoxal
/
Encéphale
/
Acide gamma-amino-butyrique
Limites:
Animals
Langue:
En
Journal:
J Nutr Sci Vitaminol (Tokyo)
Année:
1978
Type de document:
Article