A specific immunoradiometric assay of cationic trypsin(ogen) that does not recognize trypsin-alpha-1-proteinase inhibitor complex.
Clin Chim Acta
; 235(2): 197-206, 1995 Mar 31.
Article
de En
| MEDLINE
| ID: mdl-7554274
ABSTRACT
An immunoradiometric assay using two monoclonal antibodies directed to human trypsin 1 was developed for measuring trypsin(ogen) in biological fluids. The assay is different from other assays in that it is specific for cationic trypsinogen and does not recognize the alpha-1-proteinase inhibitor-trypsin complex. It can be used as a complement to classical immunoassays to characterize trypsinogen activation in pathological cases. The evaluation and the specificity of the assay are presented.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Trypsinogène
/
Alpha-Globulines
/
Trypsine
/
Dosage radioimmunométrique
/
Inhibiteurs trypsiques
Limites:
Animals
/
Humans
Langue:
En
Journal:
Clin Chim Acta
Année:
1995
Type de document:
Article
Pays d'affiliation:
France