Genomic sequence of mouse COL1A1 encoding the collagen propeptides.
Biochim Biophys Acta
; 1216(3): 469-74, 1993 Dec 14.
Article
de En
| MEDLINE
| ID: mdl-8268229
ABSTRACT
The nucleotide sequences of the mouse pro alpha 1(I) gene regions coding for the N- and C-propeptides is reported. The exon-intron structure was highly homologous to human COL1A1 and the deduced amino acid sequences of the N- and C-propeptides showed 67% and 91% identity with the human sequence. This gene sequence information will allow the production of specific gene mutations by site-directed mutagenesis to study the structure and function of these important propeptide domains.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Procollagène
/
Souris
Limites:
Animals
/
Humans
Langue:
En
Journal:
Biochim Biophys Acta
Année:
1993
Type de document:
Article
Pays d'affiliation:
Australie