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Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate.
Cook, P F; Tai, C H; Hwang, C C; Woehl, E U; Dunn, M F; Schnackerz, K D.
Affiliation
  • Cook PF; Department of Biochemistry and Molecular Biology, University of North Texas Health Science Center, Fort Worth, Texas 76107-2699, USA.
J Biol Chem ; 271(42): 25842-9, 1996 Oct 18.
Article de En | MEDLINE | ID: mdl-8824215
Recherche sur Google
Collection: 01-internacional Base de données: MEDLINE Sujet principal: Phosphate de pyridoxal / Salmonella typhimurium / O-acetylserine(thiol)-lyase / Alanine Langue: En Journal: J Biol Chem Année: 1996 Type de document: Article Pays d'affiliation: États-Unis d'Amérique
Recherche sur Google
Collection: 01-internacional Base de données: MEDLINE Sujet principal: Phosphate de pyridoxal / Salmonella typhimurium / O-acetylserine(thiol)-lyase / Alanine Langue: En Journal: J Biol Chem Année: 1996 Type de document: Article Pays d'affiliation: États-Unis d'Amérique