Spectrum of clinical and cardiac dysfunction in bronchopulmonary dysplasia: early prediction of long-term morbidity.
J Perinatol
; 17(2): 95-100, 1997.
Article
de En
| MEDLINE
| ID: mdl-9134505
ABSTRACT
OBJECTIVES:
The objective of this study was to correlate the severity of bronchopulmonary dysplasia (BPD) in infants < or = 28 weeks' gestation with clinical and radiologic scoring and cardiac function as measured by echocardiography. STUDYDESIGN:
Twenty-five infants with a mean birth weight of 909 gm and gestational age 26 weeks were studied. All infants were categorized with a clinical and radiologic scoring system at 1 and 3 months. All infants were studied with two-dimensional, M-mode, and Doppler echocardiography.RESULTS:
A significant correlation was found between clinical and radiologic scores at 1 month (r = 0.42) and between radiologic scorings at 1 and 3 months (r = 0.67). Severe BPD is directly related with mean airway pressure on day 7 of life (p < 0.05), use of intralipids (p < 0.05), and average oxygen exposure (p < 0.05). Left ventricular posterior wall thickness is directly correlated to severity of BPD (p < 0.05), and transmitral flow velocities and early diastolic/atrial contraction flow velocity ratio are inversely related to severity of BPD (p < 0.05).CONCLUSIONS:
Severe BPD can be predicted at an early age, and certain subtle cardiac dysfunctions can be used as early markers of BPD.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Dysplasie bronchopulmonaire
/
Prématuré
/
Cardiomégalie
Type d'étude:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Female
/
Humans
/
Infant
/
Male
/
Newborn
Langue:
En
Journal:
J Perinatol
Sujet du journal:
PERINATOLOGIA
Année:
1997
Type de document:
Article
Pays d'affiliation:
Australie