Purine salvage rescue by xanthine-guanine phosphoribosyltransferase (XGPRT) potentiates methotrexate resistance conferred by transfer of a mutated dihydrofolate reductase gene.

Mineishi, S; Nakahara, S; Takebe, N; Zhao, S C; Banerjee, D; Bertino, J R

Mineishi, S; Nakahara, S; Takebe, N; Zhao, S C; Banerjee, D; Bertino, J R.

Affiliation

Mineishi S; Program of Molecular Pharmacology and Experimental Therapeutics and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. sxm@heme.medicine.wisc.edu

Cancer Gene Ther ; 5(3): 144-9, 1998.

Article de En | MEDLINE | ID: mdl-9622097

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Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pentosyltransferases / Purines / Dihydrofolate reductase / Méthotrexate / Techniques de transfert de gènes / Antimétabolites antinéoplasiques Limites: Animals Langue: En Journal: Cancer Gene Ther Sujet du journal: GENETICA MEDICA / NEOPLASIAS / TERAPEUTICA Année: 1998 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

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