Induction of ovarian tumors by heavy ion irradiation in B6C3F1 mice.
Oncol Rep
; 5(6): 1377-80, 1998.
Article
de En
| MEDLINE
| ID: mdl-9769371
ABSTRACT
Six-week-old B6C3F1 mice were exposed to 0.439 Gy heavy ion irradiation as a 290 MeV/u carbon-ion beam (LET 10 keV/micron) at 2 cm from the upper proximal point of a spread Bragg beam and autopsied 13.5 months after the irradiation. In males total tumor incidences, mainly liver tumors, were 37.0% in irradiated group and 25.0% in control (P>0.05). In females the total tumor incidences were 32.3%, mainly ovarian tumors, in the irradiated group and 0% in the controls. These results indicate that heavy ion irradiation induces ovarian tumors in females but does not target any organ in males.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs de l'ovaire
/
Tumeurs du foie
/
Tumeurs radio-induites
Limites:
Animals
Langue:
En
Journal:
Oncol Rep
Sujet du journal:
NEOPLASIAS
Année:
1998
Type de document:
Article
Pays d'affiliation:
Japon