Molecular mimicry in chronic inflammatory demyelinating polyneuropathy and melanoma.
Neurology
; 51(6): 1738-41, 1998 Dec.
Article
de En
| MEDLINE
| ID: mdl-9855537
ABSTRACT
Polyclonal immunoglobulin M antibodies to the monosialoganglioside GM2, sulfoglucuronyl glycolipids, and sulfatide were detected by thin-layer chromatography and enzyme-linked immunosorbent assay in the serum of a patient with melanoma and chronic inflammatory demyelinating polyneuropathy. Both the patient's serum and polyclonal antibodies against GM2 reacted strongly with a biopsy of melanomatous tissue from the patient, suggesting a process of molecular mimicry.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Polyneuropathies
/
Maladies démyélinisantes
/
Mimétisme moléculaire
/
Ganglioside GM1
/
Mélanome
Limites:
Aged
/
Female
/
Humans
Langue:
En
Journal:
Neurology
Année:
1998
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique