Protective effect of injection of Danhong against acute myocardial ischemia in dogs / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1463-1465, 2008.
Article
de Zh
| WPRIM
| ID: wpr-264854
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the protective effects of injection of Danhong against acute myocardial ischemia in dogs.</p><p><b>METHOD</b>The myocardial ischemia model were established by ligation of coronary artery in dogs. The degree of myocardial ischemia and the myocardial infarction size were observed before and after giving injection of Danhong. The serum creatine phosphokinase (CK) and lactate dehydrogenase (LDH) activities were also determined.</p><p><b>RESULT</b>Injection of Danhong (1, 2, 4 g x kg(-1)) could significantly decreased the damage degree of myocardial ischemia, redused myocardial infarction size and also reduced the serum LDH and CK activities.</p><p><b>CONCLUSION</b>Injection of Danhong had protective action on myocardial ischemia.</p>
Texte intégral:
1
Base de données:
WPRIM
Sujet principal:
Anatomopathologie
/
Pharmacologie
/
Sang
/
Médicaments issus de plantes chinoises
/
Ischémie myocardique
/
Creatine kinase
/
Traitement médicamenteux
/
Injections
/
L-Lactate dehydrogenase
/
Infarctus du myocarde
Limites:
Animals
Langue:
Zh
Journal:
China Journal of Chinese Materia Medica
Année:
2008
Type de document:
Article