Study of huchang qingfei pellets on immune function in rats infected with Mycoplasma pneumoniae / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the effects and mechanism of Huchang Qingfei pellets on immune function in rats infected with mycoplasma pneumoniae.</p><p><b>METHOD</b>A rat model of mycoplasmal pneumonia (MP) was developed in repeated intranasal infectious routes and then the humoral and cellular immunocompetences were detected by radioimmunoassay, immune-turbidimetry and flow cytometry.</p><p><b>RESULT</b>The levels of serum IgG,IgM and IL-2, IL-6 were enhinced obviously, the complement C3 and TNF-alpha were decreased and the ratio of CD4+ /CD8+ was improved significantly in the Huchang groups as compared with MP model group.</p><p><b>CONCLUSION</b>Huchang Qingfei pellets can reinforce immune function via preventing both cellular and humoral immunity from depression in the rats with MP.</p>