Relationship between serum adiponectin and bone mineral density in preterm infants / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 58-62, 2015.
Article
de Zh
| WPRIM
| ID: wpr-289469
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To examine serum adiponectin level in preterm infants and to evaluate the relationship between serum adiponectin and bone mineral density in preterm infants.</p><p><b>METHODS</b>Seventy-two appropriate-for-gestational-age neonates were classified into three groups according to their gestational ages: early preterm (31-33(+6) weeks, 13 cases), late preterm (34-36(+6) weeks, 16 cases), and full-term (37-42 weeks, 43 cases). Venous blood was collected at one week of their life to measure serum adiponectin concentration. During the period, omnisense ultrasound bone sonometer was applied to measure speed of sound (SOS) of the left tibia.</p><p><b>RESULTS</b>The median of tibia SOS in the early preterm group was significantly lower than in the late preterm and full term groups (P<0.05), and the median of tibia SOS in the late preterm group was lower than in the full-term group (P<0.05). Serum adiponectin level was lowest in the early preterm group, and the full-term group had the highest serum adiponectin level. Serum adiponectin level was positively correlated with tibia SOS in preterm infants (r=0.664, P<0.05). According to the result of multivariate linear stepwise regression analysis, serum adiponectin and birth weight were independent predictor of tibia SOS in preterm infants.</p><p><b>CONCLUSIONS</b>Serum adiponectin level is lower in preterm infants than that in full-term infants. There is a positive correlation between serum adiponectin and bone mineral density in preterm infants.</p>
Texte intégral:
1
Base de données:
WPRIM
Sujet principal:
Poids de naissance
/
Sang
/
Prématuré
/
Densité osseuse
/
Modèles linéaires
/
Adiponectine
Type d'étude:
Prognostic_studies
Limites:
Female
/
Humans
/
Male
/
Newborn
Langue:
Zh
Journal:
Chinese Journal of Contemporary Pediatrics
Année:
2015
Type de document:
Article