Effects of matrine on structure and function of K562 cells / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
; (53): 2788-2789, 2003.
Article
de Zh
| WPRIM
| ID: wpr-410093
Bibliothèque responsable:
WPRO
ABSTRACT
Aim To investigate the effect of matrine on cytoskeletonof K562 cells. Methods Micropipette aspiration technique was adoptedto investigate the viscoelasticity of K562 cells, while the different ex-pression of cytoskeletal protein gene was analyzed by DNA microar-ray. Results In matrine-treated K562 cells, the viscoelastic propertiesKI, K2 and were decreased significantly from 726 ± 215 to 432 ±67,433 ±119 to 242±31, 72±38 to 50±15 respectively, and the geneexpression of prefoldin and ezrin was much stronger than that of controlcells. Conclusion The strueture and function can be changed in ma-trine-treated K562 cells.
Texte intégral:
1
Base de données:
WPRIM
Langue:
Zh
Journal:
Chinese Journal of Tissue Engineering Research
Année:
2003
Type de document:
Article